New ICD-10-CM Codes in 2021 2020 2019 2018 2017 2016

New ICD-10-CM Codes in

619 codes were added to the 2021 ICD-10-CM code set, effective October 1, 2020.

Displaying codes 1-100 of 619:

2021 ICD-10-CM Diagnosis Code A84.81

Powassan virus disease

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code A84.89

Other tick-borne viral encephalitis

    2021 - New Code Billable/Specific Code
Applicable To
  • Louping ill
Code First
  • , if applicable, transfusion related infection (T80.22-)
2021 ICD-10-CM Diagnosis Code B60.00

Babesiosis, unspecified

    2021 - New Code Billable/Specific Code
Applicable To
  • Babesiosis due to unspecified Babesia species
  • Piroplasmosis, unspecified
2021 ICD-10-CM Diagnosis Code B60.01

Babesiosis due to Babesia microti

    2021 - New Code Billable/Specific Code
Applicable To
  • Infection due to B. microti
2021 ICD-10-CM Diagnosis Code B60.02

Babesiosis due to Babesia duncani

    2021 - New Code Billable/Specific Code
Applicable To
  • Infection due to B. duncani and B. duncani-type species
2021 ICD-10-CM Diagnosis Code B60.03

Babesiosis due to Babesia divergens

    2021 - New Code Billable/Specific Code
Applicable To
  • Babesiosis due to Babesia MO-1
  • Infection due to B. divergens and B. divergens-like strains
2021 ICD-10-CM Diagnosis Code B60.09

Other babesiosis

    2021 - New Code Billable/Specific Code
Applicable To
  • Babesiosis due to Babesia KO-1
  • Babesiosis due to Babesia venatorum
  • Infection due to other Babesia species
  • Infection due to other protozoa of the order Piroplasmida
  • Other piroplasmosis
2021 ICD-10-CM Diagnosis Code D57.03

Hb-SS disease with cerebral vascular involvement

    2021 - New Code Billable/Specific Code
Code Also
  • , if applicable, cerebral infarction (I63.-)
2021 ICD-10-CM Diagnosis Code D57.09

Hb-SS disease with crisis with other specified complication

    2021 - New Code Billable/Specific Code
Use Additional
  • code to identify complications, such as:
  • cholelithiasis (K80.-)
  • priapism (N48.32)
2021 ICD-10-CM Diagnosis Code D57.213

Sickle-cell/Hb-C disease with cerebral vascular involvement

    2021 - New Code Billable/Specific Code
Code Also
  • , if applicable, cerebral infarction (I63.-)
2021 ICD-10-CM Diagnosis Code D57.218

Sickle-cell/Hb-C disease with crisis with other specified complication

    2021 - New Code Billable/Specific Code
Use Additional
  • code to identify complications, such as:
  • cholelithiasis (K80.-)
  • priapism (N48.32)
2021 ICD-10-CM Diagnosis Code D57.413

Sickle-cell thalassemia, unspecified, with cerebral vascular involvement

    2021 - New Code Billable/Specific Code
Code Also
  • , if applicable cerebral infarction (I63.-)
2021 ICD-10-CM Diagnosis Code D57.418

Sickle-cell thalassemia, unspecified, with crisis with other specified complication

    2021 - New Code Billable/Specific Code
Use Additional
  • code to identify complications, such as:
  • cholelithiasis (K80.-)
  • priapism (N48.32)
2021 ICD-10-CM Diagnosis Code D57.42

Sickle-cell thalassemia beta zero without crisis

    2021 - New Code Billable/Specific Code
Applicable To
  • HbS-beta zero without crisis
  • Sickle-cell beta zero without crisis
2021 ICD-10-CM Diagnosis Code D57.43

Sickle-cell thalassemia beta zero with crisis

    2021 - New Code Non-Billable/Non-Specific Code
Applicable To
  • HbS-beta zero with crisis
  • Sickle-cell beta zero with crisis
2021 ICD-10-CM Diagnosis Code D57.431

Sickle-cell thalassemia beta zero with acute chest syndrome

    2021 - New Code Billable/Specific Code
Applicable To
  • HbS-beta zero with acute chest syndrome
  • Sickle-cell beta zero with acute chest syndrome
2021 ICD-10-CM Diagnosis Code D57.432

Sickle-cell thalassemia beta zero with splenic sequestration

    2021 - New Code Billable/Specific Code
Applicable To
  • HbS-beta zero with splenic sequestration
  • Sickle-cell beta zero with splenic sequestration
2021 ICD-10-CM Diagnosis Code D57.433

Sickle-cell thalassemia beta zero with cerebral vascular involvement

    2021 - New Code Billable/Specific Code
Applicable To
  • HbS-beta zero with cerebral vascular involvement
  • Sickle-cell beta zero with cerebral vascular involvement
Code Also
  • , if applicable cerebral infarction (I63.-)
2021 ICD-10-CM Diagnosis Code D57.438

Sickle-cell thalassemia beta zero with crisis with other specified complication

    2021 - New Code Billable/Specific Code
Applicable To
  • HbS-beta zero with other specified complication
  • Sickle-cell beta zero with other specified complication
Use Additional
  • code to identify complications, such as:
  • cholelithiasis (K80.-)
  • priapism (N48.32)
2021 ICD-10-CM Diagnosis Code D57.439

Sickle-cell thalassemia beta zero with crisis, unspecified

    2021 - New Code Billable/Specific Code
Applicable To
  • HbS-beta zero with other specified complication
  • Sickle-cell beta zero with crisis unspecified
  • Sickle-cell thalassemia beta zero with (painful) crisis NOS
  • Sickle-cell thalassemia beta zero with vasoocclusive pain
2021 ICD-10-CM Diagnosis Code D57.44

Sickle-cell thalassemia beta plus without crisis

    2021 - New Code Billable/Specific Code
Applicable To
  • HbS-beta plus without crisis
  • Sickle-cell beta plus without crisis
2021 ICD-10-CM Diagnosis Code D57.45

Sickle-cell thalassemia beta plus with crisis

    2021 - New Code Non-Billable/Non-Specific Code
Applicable To
  • HbS-beta plus with crisis
  • Sickle-cell beta plus with crisis
2021 ICD-10-CM Diagnosis Code D57.451

Sickle-cell thalassemia beta plus with acute chest syndrome

    2021 - New Code Billable/Specific Code
Applicable To
  • HbS-beta plus with acute chest syndrome
  • Sickle-cell beta plus with acute chest syndrome
2021 ICD-10-CM Diagnosis Code D57.452

Sickle-cell thalassemia beta plus with splenic sequestration

    2021 - New Code Billable/Specific Code
Applicable To
  • HbS-beta plus with splenic sequestration
  • Sickle-cell beta plus with splenic sequestration
2021 ICD-10-CM Diagnosis Code D57.453

Sickle-cell thalassemia beta plus with cerebral vascular involvement

    2021 - New Code Billable/Specific Code
Applicable To
  • HbS-beta plus with cerebral vascular involvement
  • Sickle-cell beta plus with cerebral vascular involvement
Code Also
  • , if applicable cerebral infarction (I63.-)
2021 ICD-10-CM Diagnosis Code D57.458

Sickle-cell thalassemia beta plus with crisis with other specified complication

    2021 - New Code Billable/Specific Code
Applicable To
  • HbS-beta plus with crisis with other specified complication
  • Sickle-cell beta plus with crisis with other specified complication
Use Additional
  • code to identify complications, such as:
  • cholelithiasis (K80.-)
  • priapism (N48.32)
2021 ICD-10-CM Diagnosis Code D57.459

Sickle-cell thalassemia beta plus with crisis, unspecified

    2021 - New Code Billable/Specific Code
Applicable To
  • HbS-beta plus with crisis with unspecified complication
  • Sickle-cell beta plus with crisis with unspecified complication
  • Sickle-cell thalassemia beta plus with (painful) crisis NOS
  • Sickle-cell thalassemia beta plus with vasoocclusive pain
2021 ICD-10-CM Diagnosis Code D57.813

Other sickle-cell disorders with cerebral vascular involvement

    2021 - New Code Billable/Specific Code
Code Also
  • , if applicable: cerebral infarction (I63.-)
2021 ICD-10-CM Diagnosis Code D57.818

Other sickle-cell disorders with crisis with other specified complication

    2021 - New Code Billable/Specific Code
Use Additional
  • code to identify complications, such as:
  • cholelithiasis (K80.-)
  • priapism (N48.32)
2021 ICD-10-CM Diagnosis Code D59.10

Autoimmune hemolytic anemia, unspecified

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code D59.11

Warm autoimmune hemolytic anemia

    2021 - New Code Billable/Specific Code
Applicable To
  • Warm type (primary) (secondary) (symptomatic) autoimmune hemolytic anemia
  • Warm type autoimmune hemolytic disease
2021 ICD-10-CM Diagnosis Code D59.12

Cold autoimmune hemolytic anemia

    2021 - New Code Billable/Specific Code
Applicable To
  • Chronic cold hemagglutinin disease
  • Cold agglutinin disease
  • Cold agglutinin hemoglobinuria
  • Cold type (primary) (secondary) (symptomatic) autoimmune hemolytic anemia
  • Cold type autoimmune hemolytic disease
2021 ICD-10-CM Diagnosis Code D59.13

Mixed type autoimmune hemolytic anemia

    2021 - New Code Billable/Specific Code
Applicable To
  • Mixed type autoimmune hemolytic disease
  • Mixed type, cold and warm, (primary) (secondary) (symptomatic) autoimmune hemolytic anemia
2021 ICD-10-CM Diagnosis Code D59.19

Other autoimmune hemolytic anemia

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code D72.10

Eosinophilia, unspecified

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code D72.11

Hypereosinophilic syndrome [HES]

    2021 - New Code Non-Billable/Non-Specific Code
2021 ICD-10-CM Diagnosis Code D72.110

Idiopathic hypereosinophilic syndrome [IHES]

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code D72.111

Lymphocytic Variant Hypereosinophilic Syndrome [LHES]

    2021 - New Code Billable/Specific Code
Applicable To
  • Lymphocyte variant hypereosinophilia
Code Also
  • , if applicable, any associated lymphocytic neoplastic disorder
2021 ICD-10-CM Diagnosis Code D72.118

Other hypereosinophilic syndrome

    2021 - New Code Billable/Specific Code
Applicable To
  • Episodic angioedema with eosinophilia
  • Gleich's syndrome
2021 ICD-10-CM Diagnosis Code D72.119

Hypereosinophilic syndrome [HES], unspecified

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code D72.12

Drug rash with eosinophilia and systemic symptoms syndrome

    2021 - New Code Billable/Specific Code
Applicable To
  • DRESS syndrome
Use Additional
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
2021 ICD-10-CM Diagnosis Code D72.18

Eosinophilia in diseases classified elsewhere

    2021 - New Code Billable/Specific Code
Code First
  • underlying disease, such as:
  • chronic myelomonocytic leukemia (C93.1-)
2021 ICD-10-CM Diagnosis Code D72.19

Other eosinophilia

    2021 - New Code Billable/Specific Code
Applicable To
  • Familial eosinophilia
  • Hereditary eosinophilia
2021 ICD-10-CM Diagnosis Code D84.81

Immunodeficiency due to conditions classified elsewhere

    2021 - New Code Billable/Specific Code
Code First
  • underlying condition, such as:
  • chromosomal abnormalities (Q90-Q99)
  • diabetes mellitus (E08-E13)
  • malignant neoplasms (C00-C96)
Type 1 Excludes
  • certain disorders involving the immune mechanism (D80-D83, D84.0, D84.1, D84.9)
  • human immunodeficiency virus [HIV] disease (B20)
2021 ICD-10-CM Diagnosis Code D84.82

Immunodeficiency due to drugs and external causes

    2021 - New Code Non-Billable/Non-Specific Code
2021 ICD-10-CM Diagnosis Code D84.821

Immunodeficiency due to drugs

    2021 - New Code Billable/Specific Code
Applicable To
  • Immunodeficiency due to (current or past) medication
Use Additional
  • code for adverse effect if applicable, to identify adverse effect of drug (T36-T50 with fifth or six character 5)
2021 ICD-10-CM Diagnosis Code D84.822

Immunodeficiency due to external causes

    2021 - New Code Billable/Specific Code
Code Also
  • , if applicable, radiological procedure and radiotherapy (Y84.2)
Use Additional
  • code for external cause such as:
  • exposure to ionizing radiation (W88)
2021 ICD-10-CM Diagnosis Code D84.89

Other immunodeficiencies

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code D89.83

Cytokine release syndrome

    2021 - New Code Non-Billable/Non-Specific Code
Code First
  • underlying cause, such as:
  • complications following infusion, transfusion and therapeutic injection (T80.89-)
  • complications of transplanted organs and tissue (T86.-)
Use Additional
  • code to identify associated manifestations
2021 ICD-10-CM Diagnosis Code D89.831

Cytokine release syndrome, grade 1

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code D89.832

Cytokine release syndrome, grade 2

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code D89.833

Cytokine release syndrome, grade 3

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code D89.834

Cytokine release syndrome, grade 4

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code D89.835

Cytokine release syndrome, grade 5

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code D89.839

Cytokine release syndrome, grade unspecified

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code E70.81

Aromatic L-amino acid decarboxylase deficiency

    2021 - New Code Billable/Specific Code
Applicable To
  • AADC deficiency
2021 ICD-10-CM Diagnosis Code E70.89

Other disorders of aromatic amino-acid metabolism

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code E74.81

Disorders of glucose transport, not elsewhere classified

    2021 - New Code Non-Billable/Non-Specific Code
2021 ICD-10-CM Diagnosis Code E74.810

Glucose transporter protein type 1 deficiency

    2021 - New Code Billable/Specific Code
Applicable To
  • De Vivo syndrome
  • Glucose transport defect, blood-brain barrier
  • Glut1 deficiency
  • GLUT1 deficiency syndrome 1, infantile onset
  • GLUT1 deficiency syndrome 2, childhood onset
2021 ICD-10-CM Diagnosis Code E74.818

Other disorders of glucose transport

    2021 - New Code Billable/Specific Code
Applicable To
  • (Familial) renal glycosuria
2021 ICD-10-CM Diagnosis Code E74.819

Disorders of glucose transport, unspecified

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code E74.89

Other specified disorders of carbohydrate metabolism

    2021 - New Code Billable/Specific Code
Applicable To
  • Essential pentosuria
2021 ICD-10-CM Diagnosis Code F10.13

Alcohol abuse, with withdrawal

    2021 - New Code Non-Billable/Non-Specific Code
2021 ICD-10-CM Diagnosis Code F10.130

Alcohol abuse with withdrawal, uncomplicated

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code F10.131

Alcohol abuse with withdrawal delirium

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code F10.132

Alcohol abuse with withdrawal with perceptual disturbance

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code F10.139

Alcohol abuse with withdrawal, unspecified

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code F10.93

Alcohol use, unspecified with withdrawal

    2021 - New Code Non-Billable/Non-Specific Code
2021 ICD-10-CM Diagnosis Code F10.930

Alcohol use, unspecified with withdrawal, uncomplicated

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code F10.931

Alcohol use, unspecified with withdrawal delirium

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code F10.932

Alcohol use, unspecified with withdrawal with perceptual disturbance

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code F10.939

Alcohol use, unspecified with withdrawal, unspecified

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code F11.13

Opioid abuse with withdrawal

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code F12.13

Cannabis abuse with withdrawal

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code F13.13

Sedative, hypnotic or anxiolytic abuse with withdrawal

    2021 - New Code Non-Billable/Non-Specific Code
2021 ICD-10-CM Diagnosis Code F13.130

Sedative, hypnotic or anxiolytic abuse with withdrawal, uncomplicated

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code F13.131

Sedative, hypnotic or anxiolytic abuse with withdrawal delirium

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code F13.132

Sedative, hypnotic or anxiolytic abuse with withdrawal with perceptual disturbance

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code F13.139

Sedative, hypnotic or anxiolytic abuse with withdrawal, unspecified

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code F14.13

Cocaine abuse, unspecified with withdrawal

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code F14.93

Cocaine use, unspecified with withdrawal

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code F15.13

Other stimulant abuse with withdrawal

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code F19.13

Other psychoactive substance abuse with withdrawal

    2021 - New Code Non-Billable/Non-Specific Code
2021 ICD-10-CM Diagnosis Code F19.130

Other psychoactive substance abuse with withdrawal, uncomplicated

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code F19.131

Other psychoactive substance abuse with withdrawal delirium

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code F19.132

Other psychoactive substance abuse with withdrawal with perceptual disturbance

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code F19.139

Other psychoactive substance abuse with withdrawal, unspecified

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code G11.10

Early-onset cerebellar ataxia, unspecified

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code G11.11

Friedreich ataxia

    2021 - New Code Billable/Specific Code
Applicable To
  • Autosomal recessive Friedreich ataxia
  • Friedreich ataxia with retained reflexes
2021 ICD-10-CM Diagnosis Code G11.19

Other early-onset cerebellar ataxia

    2021 - New Code Billable/Specific Code
Applicable To
  • Early-onset cerebellar ataxia with essential tremor
  • Early-onset cerebellar ataxia with myoclonus [Hunt's ataxia]
  • Early-onset cerebellar ataxia with retained tendon reflexes
  • X-linked recessive spinocerebellar ataxia
2021 ICD-10-CM Diagnosis Code G40.42

Cyclin-Dependent Kinase-Like 5 Deficiency Disorder

    2021 - New Code Billable/Specific Code
Applicable To
  • CDKL5
Use Additional
  • code, if known, to identify associated manifestations, such as:
  • cortical blindness (H47.61-)
  • global developmental delay (F88)
2021 ICD-10-CM Diagnosis Code G40.83

Dravet syndrome

    2021 - New Code Non-Billable/Non-Specific Code
Applicable To
  • Polymorphic epilepsy in infancy (PMEI)
  • Severe myoclonic epilepsy in infancy (SMEI)
2021 ICD-10-CM Diagnosis Code G40.833

Dravet syndrome, intractable, with status epilepticus

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code G40.834

Dravet syndrome, intractable, without status epilepticus

    2021 - New Code Billable/Specific Code
Applicable To
  • Dravet syndrome NOS
2021 ICD-10-CM Diagnosis Code G71.20

Congenital myopathy, unspecifed

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code G71.21

Nemaline myopathy

    2021 - New Code Billable/Specific Code
2021 ICD-10-CM Diagnosis Code G71.22

Centronuclear myopathy

    2021 - New Code Non-Billable/Non-Specific Code
2021 ICD-10-CM Diagnosis Code G71.220

X-linked myotubular myopathy

    2021 - New Code Billable/Specific Code
Applicable To
  • Myotubular (centronuclear) myopathy
2021 ICD-10-CM Diagnosis Code G71.228

Other centronuclear myopathy

    2021 - New Code Billable/Specific Code
Applicable To
  • Autosomal centronuclear myopathy
  • Autosomal dominant centronuclear myopathy
  • Autosomal recessive centronuclear myopathy
  • Centronuclear myopathy, NOS
2021 ICD-10-CM Diagnosis Code G71.29

Other congenital myopathy

    2021 - New Code Billable/Specific Code
Applicable To
  • Central core disease
  • Minicore disease
  • Multicore disease
  • Multiminicore disease